INDUSTRIAL UNIVERSITY OF HO CHI MINH CITY
INSTITUTE OF BIOTECHNOLOGY AND FOOD TECHNOLOGY
Vu Thanh Ngoc
Vu Thanh Ngoc

CIRRICULUM VITAE

Ngoc T. Vu, PhD

Lecturer

Institute of Biotechnology and Food Technology

Industrial University of Hochiminh City

PERSONAL

Address: Industrial University of Hochiminh City, Room F4-07

E-mail: vuthanhngoc@iuh.edu.vn

EDUCATION

2014: PhD in Biochemistry and Molecular Biology (Advisor: Dr. Chalfant, Charles), VIRGINIA COMMONWEALTH UNIVERSITY, USA

2009: Bachelor of Engineering in Biotechnology, VIETNAM NATIONAL UNIVERSITY

WORK EXPERIENCE

2014-2016: Postdoctoral Researcher, Dept. of Biochemistry and Molecular Biology, Virginia Commonwealth University, USA (Advisors: Dr. Chalfant, Charles)

2011-2014: Researcher, Virginia Commonwealth University School of Medicine, USA

2010-2014: Teaching Assistant, Virginia Commonwealth University School of Medicine, USA

2009-2010: Research Assistant, Hochiminh Biotech Center, Vietnam (Advisors: Dr. Nguyen, Binh)

SCIENTIFIC PROJECTS PARTICIPATED

Project title Time Principal investigator
Development of recombinant vaccines against avian influenza 2009-2010 Dr. Binh Nguyen,
HCMC Biotech Center
Novel action of the pro-drug FTY720 as an HDAC inhibitor that sensitizes breast carcinoma cells to chemotherapy 2010 Dr. Sarah Spiegel,
Virginia Commonwealth University
Construction of TDP1 targeting vector to generate TDP1-knockout stem cells and restoration of normal TDP1 expression in SCAN1 cells 2011 Dr. Lawrence Povirk,
Virginia Commonwealth University
Regulation and mechanistic functions of caspase-9 splicing 2011-2016 Dr. Charles Chalfant,
Virginia Commonwealth University
Mechanistic roles of caspase-9b in the tumorigensis of non-small cell lung cancer cells 2012-2016 Dr. Charles Chalfant,
Virginia Commonwealth University
Regulation and mechanistic functions of Bclx splicing 2014-2016 Dr. Charles Chalfant,
Virginia Commonwealth University
Regulation and mechanistic roles of CPEB2 splicing 2014-2016 Dr. Charles Chalfant,
Virginia Commonwealth University
Enzymatic activity and mechanistic functions of cPLA2α in lipid signaling 2015-2016 Dr. Charles Chalfant,
Virginia Commonwealth University

PUBLICATIONS

Full articles in peer-reviewed journals

Accepted, in press, or published

  1. Caspase-9b interacts directly with cIAP1 to drive agonist-independent activation of NF- B and lung tumorigenesis. Vu N. T., Park M. A., Shultz M. D., Bulut G. B., Ladd A. C., Chalfant C. E. (2016) Cancer Res.
  2. Melanoma differentiation associated gene 7/IL-24 exerts cytotoxic effects by altering the alternative splicing of Bcl-x pre-mRNA via the SRC/PKCδ signaling axis. Vu N. T., Shapiro B. A., Shultz M. D., Shultz J. C, Mietla J. A., Gouda M. M., Yacoub A., Dent P., Fisher P. B., Park M. A., Chalfant C. E. (2016) J. Bio. Chem.
  3. The alternative splicing of cytoplasmic polyadenylation element binding protein 2 drives anoikis resistance and the metastasis of triple negative breast cancer. Johnson R. M., Vu N. T., Griffin B. P., Gentry A. E., Archer K. J., Chalfant C. E., Park M. A. (2015). J. Bio. Chem.
  4. hnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L. Vu N. T., Park M. A., Shultz J. C., Goehe R. W., Hoeferlin L. A., Shultz M. D., Smith S. A., Lynch K. W., Chalfant C. E. (2013) J. Bio. Chem.
  5. The Proto-oncogene PKCι regulates the alternative splicing of Bcl-x pre-mRNA. Shultz J. C., Vu N.Shultz M. D., Mba M. U., Shapiro B. A., Chalfant C. E. (2012) Mol. Cancer Res.

PRESENTATIONS AT SCIENTIFIC MEETINGS

  1. Poster presentation, 2015 Cancer Research Retreat, Virginia Commonwealth University Massey Cancer Center, USA

Caspase-9b directly interacts with cIAP1 to drive agonist-independent NF-kB activation and tumorigenesis in non-small cell lung cancer. Vu N. T., Park M. A., Shultz M. D., Ladd A. C., Chalfant C. E.

  1. Poster presentation, 2015, AACR Annual Meeting, USA

Caspase-9b directly interacts with cIAP1 to drive agonist-independent NF-kB activation and tumorigenesis in non-small cell lung cancer. Vu N. T., Park M. A., Shultz M. D., Ladd A. C., Chalfant C. E.

  1. Poster presentation, 2015 ASBMB Annual Meeting, USA

Caspase-9b Directly Interacts with c-IAP1 to Drive an Agonist-Independent Activation of the NF-κB Pathway and the Enhancement of Tumorigenicity in Non-Small Cell Lung Cancer. Vu N. T., Park M. A., Shultz M. D., Ladd A. C., Chalfant C. E.

  1. Poster presentation, 2014 Annual Conference, Vietnam Education Foundation, USA

hnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L. Vu N. T., Park M. A., Shultz J. C., Goehe R. W., Hoeferlin L. A., Shultz M. D., Smith S. A., Lynch K. W., Chalfant C. E.

  1. Poster presentation, 2013 Daniel T. Watts Research Symposium, Medical College of Virginia, USA

hnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L. Vu N. T., Park M. A., Shultz J. C., Goehe R. W., Hoeferlin L. A., Shultz M. D., Smith S. A., Lynch K. W., Chalfant C. E.

  1. Poster presentation, 2013 Cancer Research Retreat, Virginia Commonwealth University Massey Cancer Center, USA

hnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L. Vu N. T., Park M. A., Shultz J. C., Goehe R. W., Hoeferlin L. A., Shultz M. D., Smith S. A., Lynch K. W., Chalfant C. E.

HONORS AND AWARDS

– 1st prize on poster presentation, Annual conference, Vietnam Education Foundation, 2014

– Clayton award for excellent academic achievement, School of Medicine, Virginia Commonwealth University, 2012

– Vietnam Education Foundation Fellowship for graduate study in the US, 2010

“Excellent Grade Graduation” honors with gold medal, April 2009, Vietnam National University at Ho Chi Minh City, Vietnam

– Vietnamese Government Full Scholarship for Bachelor Study, 2004-2009, Ministry of Education and Training, Vietnam

 Vallet Scholarship, “Rencontres Du Vietnam” Organization, August 2004 and August 2003

STUDENT MENTORSHIP EXPERIENCE

– Mentor for student Quoc Huynh (2015-2016). He has joined Dr. Chalfant Lab as a PhD student

– Mentor for student Daniel Stephenson (2016). He has joined Dr. Chalfant Lab as a PhD student

– Mentor for student Huy Nguyen (2015). He was a research volunteer in Dr. Chalfant Lab

SCIENTIFIC AND PROFESSIONAL SOCIETIES

– American Society for Biochemistry and Molecular Biology (ASBMB, since 2015)

American Association for Cancer Research (AACR, since 2015)

– Phi Kappa Phi Honor Society (since 2011)

– Vietnam Education Foundation Fellows and Scholars Association (VEFFA, since 2010)

 

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